Effective Date: October 1, 2025
Official Guidance: AHA Coding Clinic® for ICD-10-CM and ICD-10-PCS
The Fourth Quarter 2025 ICD-10 Coding Clinic® is now available, delivering critical updates for the year ahead. With the newsletter spanning over 100 pages, having a tool like MedKoder’s Coding Clinic® Collection is invaluable for streamlined, strategic searching. Below is a comprehensive overview of the key changes and their impact on your coding practices.
New and Revised ICD-10-CM Codes
This quarter includes 487 new ICD-10-CM codes, 38 revisions and 28 deletions, covering the following 36 topics:
- Demodex Blepharitis
- Malignant Inflammatory Neoplasm of Breast
- Leukocyte Adhesion Deficiency
- Type 2 Diabetes Mellitus without Complications, In Remission
- Hyperoxaluria
- Familial Hypercholesterolemia
- Disorders of Pyrophosphate Metabolism
- Lipodystrophy
- Primary Progressive Apraxia of Speech
- Relapsing-Remitting Multiple Sclerosis
- Limb Girdle Muscular Dystrophies (LGMD) Subtype 21/R9
- Other Inflammation of Eyelid
- Thyroid Orbitopathy
- Neovascular Glaucoma
- Fontan Circulation
- Cutaneous Abscess, Furuncle, Cellulitis, and Acute Lymphangitis of Flank
- Non-pressure Chronic Ulcers of the Skin by Site and Severity
- Abnormal Rheumatoid Factor or Anti-citrullinated Protein Antibody with and without Rheumatoid Arthritis
- Nephritic or Nephrotic Syndrome with Idiopathic and Secondary Immune Membranoproliferative Glomerulonephritis, and Hereditary Nephropathy
- Hao-Fountain Syndrome
- CTNNB1 Syndrome
- Kabuki Syndrome
- Usher Syndrome
- Genetic Disorders, Not Elsewhere Classified (QA0)
- Abdominal and Pelvic Pain
- Cannabinoid Hyperemesis Syndrome
- Costovertebral Tenderness
- Superficial Injuries, Open Wound, Laceration, Puncture, and Open Bite of the Flank
- Poisoning, Adverse Effect, and Underdosing of Fluoroquinolones
- Xylazine Toxicity
- Effects of War Theater
- Anaphylactic Reaction and Other Adverse Food Reactions to Milk and Dairy Products and Eggs
- External Cause of Injury Codes for Other Sharp Object Entering in or Through a Natural Orifice and Fishing Hook Entering Through Skin
- Blast Overpressure
- External Cause of Injury Codes for Other Outdoor Activity
- Z Codes Update
New and Revised ICD-10-PCS Codes
The FY 2026 ICD-10-PCS updates include 156 new codes and 27 deletions. Key sections include:
- Section 0: Medical and Surgical
- Stereotactic-aided Intraprocedural Neuronavigation System
- Removal and Revision of Devices in Dura and Spinal Meninges
- Insertion of Endovascular Anchors
- Bypass from the Innominate Artery
- Transfer of Vascularized Nasal Tissue
- Cricothyroidotomy
- Bypass Common Bile Duct to Duodenum
- Shoulder Arthroplasty Using the Subscapularis-Sparing Technique
- Replacement of Medial and Lateral Meniscus
- Section 5: Extracorporeal or Systemic Assistance and Performance
- Extracorporeal Circulatory Filtration
- Section 6: Extracorporeal or Systemic Therapies
- Intraoperative Donor Organ Protection in Renal Transplantation
- Section 8: Other Procedures
- Morphological Structure Analysis System
- Section F: Physical Rehabilitation and Diagnostic Audiology
- Negative Pressure Wound Therapy (NPWT)
- Section X: New Technology
- Radiofrequency Ablation of Cardiac Plexus
- Ultrasound Ablation of Brain
- Dilation Using Expandable Intraluminal Device with Growth Technology
- Dilation of Arteriovenous Fistula with Cell Impermeable Endoprosthesis
- Division of Aortic Valve Leaflets Using Radiofrequency Energy
- Dilation of Carotid Artery with Integrated Embolic Protection
- Insertion of Volume Sensor Management Device
- Temporary Transvenous Diaphragm Activation
- Insertion of Implantable Endocardiac Pacing System
- Insertion of Temporary Retrievable Intraluminal Device
- Restriction of Thoracic Aorta with Hybrid Intraluminal Device
- Inspection of Upper Gastrointestinal Tract Using Ingestible Wireless Capsule
- Sacroiliac Joint Fusion/Pelvic Fracture Fixation with Threaded Implant System
- Cervical Spinal Fusion with Custom-Made Anatomically Designed Interbody Fusion Device
- Insertion of Posterior Cervicothoracic Spinal Stabilization System
- Introduction of New Therapeutic Substances
- Introduction of Peptide Enhanced Bone Void Filler in Transforaminal Lumbar Interbody Fusion Procedures
- Transfusion of New Therapeutic Substances
- Continuous Glucose Monitoring
- Extracorporeal Pheresis of Ticagrelor
- Gene Expression Testing System for Whole Blood Samples
- Quantitative Analysis of Human Milk Macronutrient Content
- Computer-aided Triage and Notification Software for Measurement of Biomarkers
Changes to the ICD-10-CM and ICD-10-PCS Coding Guidelines
Key guideline updates this quarter include:
- The meaning of commas in the Alphabetic Index
- Coding multiple sites
- Selection and sequencing of HIV codes
- Type 2 diabetes mellitus in remission
- Prophylactic organ removal
- New examples on coding multiple procedures in the New Technology section
Ask the Editor
This issue includes 10 Q&As covering topics such as:
- Biliary Drainage Using the AXIOS™ Stent
- Malignant Inflammatory Neoplasm of Breast
- Type 2 Diabetes Mellitus without Complications, In Remission
- Abdominal and Pelvic Pain
- Cannabinoid Hyperemesis Syndrome
- Xylazine Toxicity
- Negative Pressure Wound Therapy (NPWT)
- Ultrasound Ablation of Brain
Accessing the AHA Coding Clinic
The AHA Coding Clinic serves as a vital resource for coders, offering authoritative guidance on ICD-10-CM and ICD-10-PCS coding. Accessing the full archive of Coding Clinic issues can be time-consuming and inefficient. MedKoder’s Coding Clinic® Collection provides an affordable, always-updated resource with advanced search capabilities across the entire archive, ensuring you have the information you need at your fingertips.
Preparing for 2026
As we approach 2026, it’s crucial to stay ahead of coding changes to maintain compliance and optimize reimbursement. Regularly reviewing the AHA Coding Clinic and utilizing comprehensive resources like MedKoder’s Coding Clinic® Collection can help you navigate the evolving coding landscape with confidence.